By Dr. Baker (ND)
Systemic lupus erythematosus (SLE) is a complex autoimmune condition that affects many aspects of health. It can lead to symptoms ranging from joint pain to severe organ involvement, and research suggests that underlying imbalances may contribute to the activity and progression of the disease. By identifying these potential imbalances, we can develop more personalized and comprehensive approaches to support individuals with lupus.
Nutritional Factors in Lupus
Research shows that certain nutritional deficiencies or imbalances could be involved in SLE. For example, a 2021 study found that people with lupus tend to have elevated homocysteine levels, which can increase inflammation and cardiovascular risk. Homocysteine is influenced by levels of vitamin B12 and folate, nutrients essential for regulating its metabolism. Ensuring optimal levels of these nutrients might help address factors that could exacerbate SLE symptoms.
A 2019 meta-analysis also explored the effects of vitamin D supplementation in SLE, finding that it increased vitamin D levels significantly, which may play a role in reducing fatigue in some patients. Although the exact effects on SLE disease markers were uncertain, the data suggests that vitamin D could have a supportive role. At our clinic, we can provide a thorough nutritional assessment, looking at a wide range of vitamins and minerals that may be relevant to SLE management.
Hormonal and Metabolic Factors in Lupus
SLE has also been associated with hormonal and metabolic imbalances. Research highlights a genetic connection between SLE and primary hypothyroidism, suggesting an association between these conditions (2023 study). In practical terms, this may mean that people with SLE should consider monitoring their thyroid health as part of their overall management plan. Testing hormonal markers could help reveal areas where supportive interventions may be beneficial.
Autoimmune and Immune-Related Factors
Since lupus is an autoimmune disease, immune-related markers can provide valuable insights into disease management. Serum uric acid, for instance, has shown potential as biomarkers of lupus nephritis, a severe kidney complication in SLE (2024 study). By identifying such biomarkers early, there may be opportunities for timely interventions aimed at managing disease progression.
Lifestyle and Dietary Factors
Lifestyle and diet can play significant roles in managing SLE symptoms. Some studies have suggested that dietary intake of unsaturated fatty acids, particularly omega-3s, may positively affect disease activity by reducing inflammation. A 2024 meta-analysis indicated that a diet rich in unsaturated fatty acids was associated with improved lipid profiles and reduced SLE activity scores.
Additionally, a 2022 review found that omega-3 supplements might reduce certain markers of SLE disease activity. While evidence is still emerging, incorporating foods high in unsaturated fats may benefit people with lupus. At our clinic, we provide a comprehensive dietary plan to help patients make informed choices that support their health.
Lupus and Infectious Causes
Research shows that infections like Helicobacter pylori, especially its more aggressive strains, may play a role in triggering autoimmune conditions like lupus by confusing the immune system. Studies involving thousands of patients suggest a link between H. pylori and autoimmune diseases, though it may also protect against certain stomach conditions. Our clinic includes infection screening as part of a complete approach to autoimmune care, helping us find underlying factors that support personalized treatment plans.
Screening and Monitoring for Complications
Screening for complications of lupus is critical for early detection and intervention, especially for organs frequently affected by the disease, such as the kidneys, liver, pancreas, and digestive system. Lupus nephritis is one of the most common and severe complications of lupus, so regular kidney screenings—including urine protein and creatinine tests—are essential to detect early signs of kidney damage. Liver involvement may be indicated by elevated liver enzymes, which can signal inflammation or autoimmune hepatitis. Pancreatic complications, though less common, can also be screened through enzyme tests. Additionally, lupus can affect the digestive tract, leading to symptoms such as abdominal pain and acid reflux, which may stem from inflammation or secondary autoimmune conditions affecting the gut. At our clinic, we prioritize these screenings as part of a thorough lupus management approach, helping to address complications early and personalize care effectively.
Natural Therapies for Lupus
Natural therapies can be considered alongside conventional treatments for SLE. After assessing nutritional status and identifying any deficiencies, our clinic may suggest supplements, dietary adjustments, or lifestyle strategies that align with each patient’s unique needs.
Conclusion
Before starting any intervention, it may be helpful to conduct comprehensive testing to identify individual imbalances. Personalized testing not only helps us understand the best interventions but also ensures that treatments are safe and effective for each unique case. Lupus is a multifaceted condition influenced by numerous factors, from diet to hormonal health. By addressing these areas, our clinic can work with patients to create individualized plans that aim to support their well-being.
We encourage individuals to book a consultation to explore how a comprehensive approach to SLE can potentially support a healthier and more balanced life. Our holistic approach considers a wide array of health aspects, aiming to provide a personalized path toward optimal health.
Frequently Asked Questions
Can you live a long life with lupus?
Yes, many people with lupus can live long, fulfilling lives, especially with advancements in medical understanding and care. While lupus is a chronic condition that requires ongoing management, early diagnosis and personalized treatment can greatly improve the outlook. Many factors, such as regular monitoring, lifestyle adjustments, and proactive symptom management, contribute to enhancing quality of life and longevity for those with lupus.
What is having lupus like?
Living with lupus can vary significantly from person to person. Some individuals experience only mild symptoms, while others face more severe or fluctuating issues. Common symptoms include joint pain, fatigue, skin rashes, and episodes of inflammation that can affect different organs. This variability makes lupus an unpredictable condition, and daily life may involve adapting to changes in energy levels and symptom intensity.
What are the signs of a person having lupus?
The signs of lupus can be diverse, as it is known as a "multi-system" condition that may affect multiple parts of the body. Common signs include fatigue, joint pain, and skin rashes—particularly the butterfly-shaped rash across the cheeks. Other symptoms may involve the kidneys, heart, and lungs, and can include sensitivity to sunlight, hair loss, and fevers. Because these symptoms often overlap with those of other conditions, diagnosing lupus can be challenging.
Disclaimer: This post is for informational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your healthcare provider or a qualified medical professional before starting any new treatment or if you have questions about your medical condition. While we aim to provide accurate, research-based information, individual needs and responses to treatments can vary. Our clinic offers personalized consultations to discuss health concerns and develop tailored care plans. Never disregard professional medical advice or delay seeking it because of information you have read on this site.
